About us

Fueling discoveries in personalized cancer care

Navignostics: Connecting each patient with the right drug

At Navignostics, we fight cancer by enabling personalized treatments. We analyze tumor samples and determine the best way to target each cancerous growth, so that clinicians can find the right therapy and researchers can develop new drugs.

We founded Navignostics in 2022 as a spin-off from the University of Zurich Bodenmiller Lab. We combine highly multiplex tumor imaging with advanced data analytics, and we have refined and validated our technology through rigorous research in clinical settings. Our laboratory and headquarters are located in Horgen, Switzerland.

Our approach: Spatial single-cell proteomics

The number of newly developed therapies grows every year, and cancer care is becoming more and more personalized. Most cancer treatments work by targeting certain tumor cell proteins or the interplay between tumor and immune cells. This means clinicians need to know which proteins are present on which types of cells and where they are located. This information is exactly what we provide with our spatial single-cell proteomic approach. With our highly multiplex imaging technology, we can detect and visualize up to 50 proteins from just a single tumor section. Analyzing these high-resolution images with our automated computational workflows lets us quantify an exceptional amount of information from so little tumor material.

Our technology: Multiplex imaging and advanced data analytics

Icon showing a pipette dropping a solution onto a slide, which is marked "sample"

Staining cancer tissue

Using just a single tumor tissue section, our assays detect dozens of proteins that characterize tumors. They allow us to identify individual cells, such as tumor and immune cells, and describe cancer-related processes. We do this by staining the tissues with panels of up to 50 selected metal-labeled antibodies.

Measuring metal signals

Icon shows a computer with the text "40x" in the top left hand corner. The screen shows three rectangles being superimposed over the top of each other, with three colored bars coming from the top of the computer screen.

Our imaging mass cytometry system detects all selected proteins in a single step through laser ablation of the tissue and time-of-flight measurement of the metal weights. The result is a high-resolution digital image representation of the molecular composition of the tumor.

Automated data analysis

Icon shows cells in different colours and a red line around key areas.

With our proprietary computational workflows, we gain a wealth of information on tumor features from these images. They range from single-cell protein expressions and cell types to cellular interactions and multicellular assemblies.

Clear and thorough report

A computer screen shows a molecule with a green component

Finally, we generate an easily understandable yet thorough PDF report to describe disease mechanisms. The customizable report helps clinicians make individualized treatment decisions and highlights novel signatures for cancer researchers to identify patients likely to respond to a new drug.

Two scientists wearing green overalls are talking and smiling.

Our Values

Trust in quality

We deliver consistently high quality that exceeds standards and adds value for our partners and for patients.

Stay curious

We always keep an open mind and continue to learn from new research results  to provide the best cancer care.

Grow together

We foster supportive relationships where we can learn from each other to battle cancer.

Careers at Navignostics

We are growing and are often looking for new colleagues who share our values. You can find our open positions on our LinkedIn page.

Team

Alexandra is a white woman with long, dark brown hair and brown eyes. She is smiling and wearing gold earrings and a light blue shirt.
Product Development Scientist
Andrea is a white woman with shoulder length platinum blonde hair and blue eyes. She is wearing a white and black horizontally striped jumper with a blue t-shirt underneath.
Co-Founder and COO (Chief Operations Officer)
Ben is a white man with very short mid brown hair and brown eyes. He has a short beard and wears a black jumper.
Data Scientist
Esther is a white woman with light brown wavy hair, which is tied in a half-up, half-down ponytail and light blue-grey eyes. She wears a black V-neck shirt.
Lab Scientist
Federico is a white man with lightly tanned skin, short black hair and brown eyes. He has a light beard and wears a black jumper.
Software Engineer
Ines is a white woman with long strawberry-blonde hair and light brown eyes. She wears a cobalt blue jumper.
Product Development Scientist
Jana is a white women with shoulder-length brown hair and brown eyes. She wears a black shirt and gold earrings.
Co-Founder and CEO (Chief Executive Officer)
Jilla is a white woman with long, fine straight light brown hair and light brown eyes. She wears black round glasses, a black polar neck jumper and a gold necklace.
Lab Technician
Michelle is a Latino woman with mid-length dark brown wavy hair and brown eyes. She wears a black scooped neck jumper and gold earrings
Lab Scientist
Mylène is a white woman with light brown mid-length hair and hazel-green eyes. She wears glasses, a cream scooped neck t-shirt and a necklace.
Lab Technician
Sebastian is a white man with short light brown hair and brown eyes. He wears a light blue V-neck jumper and a light blue T-shirt.
Business Development Manager
Simon is a white man with short dark hair and brown eyes. He wears brown glasses and a dark blue polo shirt.
Pathologist
Stephanie is a white man with short light brown hair, he has grey/hazel eyes and is clean-shaven. He wears a khaki t-shirt.
Co-Founder and CSO (Chief Scientific Officer)
William is a black man with black natural hair worn in long dreadlocks and dark brown eyes. He has a short beard and wears a white shirt, green and orange tartan bow tie and a green jumper.
Lab Manager

Members of the Board

Andreas Jenne, Ph.D.

Ventura

Chair of the board

Roland Diggelmann

Independent

Board member

Rohan Thakur, Ph.D.

Bruker

Board member

Bernd Bodenmiller, 
Ph.D., Prof.

Co-Founder

Board member

Frank Heppner, M.D., Prof

Think.Health

Observer

Stéphane Chevrier, Ph.D.

Co-Founder

Board member

Andrea Jacobs
&nbsp

Co-Founder

Observer

Advisory Board

Andreas Wicki, M.D., Ph.D., Prof.

University Hospital Zürich

Advisor

Holger Moch, M.D., Prof.

University Hospital Zürich

Advisor

Our Investors

We owe our progress to our investors’ trust – thank you for making our work possible. Would you like to join our journey? We are open to new investors!

Reach out to us

Come visit us, send us a letter, give us a call, drop an email, or fill out the contact form below!

Address

Phone

Email

Navignostics AG
Tödistrasse 46a
8810 Horgen

+41 44 244 09 70

Contact form